WASHINGTON (CNN) — Rick Santorum, the former Pennsylvania senator who mounted an unexpectedly strong bid for the Republican nomination in 2012, is making another bid for the White House.

Santorum will formally launch his campaign Wednesday evening in Pennsylvania, spokesman Matt Beynon confirmed to CNN.

For a politician who won the Iowa caucus in 2012 and was able to keep his campaign — fueled by support from Christian conservatives — running through the spring, Santorum is starting the 2016 race in a humble place: the bottom. He came in at 3% and 2% in the latest CNN/ORC and Fox News polls, respectively.

That’s a dramatic difference from other Republicans who have sought the nomination again after narrowly losing it in the past. John McCain and Mitt Romney, for example, began their second presidential bids in strong shape after failing to clinch the nomination in earlier bids. McCain and Romney went on to take the nomination, though they lost the general election.

Part of Santorum’s challenge is that he finds himself in a crowded field of politicians seeking the GOP nomination. He would first need to get by top evangelical vote-getters like former Gov. Mike Huckabee of Arkansas, Sen. Ted Cruz and Ben Carson if he wants to break into the broader GOP field that already includes Sens. Rand Paul of Kentucky and Marco Rubio of Florida, along with businesswoman Carly Fiorina. Other heavy-hitters, such as Wisconsin Gov. Scott Walker and former Florida Gov. Jeb Bush, will also likely get in the race this summer.

Known for his close ties to Christian conservatives, Santorum starts the 2016 race as a politician who has evolved from his days on Capitol Hill where he was known for making controversial statements about homosexuality and abortion. While he didn’t disavow those positions, Santorum began to focus more on economic populism in 2012 — a theme he will revive again in 2016. He’ll also highlight a tough foreign policy, which could appeal to many Republicans at a time of global turmoil.

Driven in part by the ISIS threat and turmoil in the Middle East and by likely Democratic nominee Hillary Clinton’s tenure as secretary of state, the 2016 campaign is shaping up to have a heavy foreign policy bend.

That’s a challenge for many Republicans who are light on foreign policy experience and Santorum is hoping voters see him as the most prepared to take on the job of commander in chief, having earned his foreign policy chops in eight years on the Senate Armed Services Committee.

And that foreign policy would be decidedly hawkish and built on neoconservative pillars: Santorum has called for 10,000 American “boots on the ground” to defeat ISIS. Other likely Republican 2016 candidates, including Jeb Bush, have been more reluctant to commit to additional ground troops in the Middle East.

Santorum is also sporting a new look. He turned heads at the Conservative Political Action Conference earlier this year with a trimmer look and more fitted suit. And the sweater vests at the center of his 2012 brand? Gone as well, aides say — for good.

Santorum will also hope to move on from the controversies that marred his last presidential effort, including comments about homosexuality and same-sex marriage, which he compared to polygamy and, years earlier, to bestiality.

If there’s anything Santorum will be looking to repeat from 2012, it’s his surprise Iowa victory, when he barnstormed through every one of the state’s 99 counties and edged past his GOP opponents.

But as he launches his presidential campaign, Santorum is without the political operative who helped steer him to victory in Iowa. Chuck Laudner, the Iowa GOP operative who crisscrossed the state with Santorum in his “Chuck Truck” and was considered crucial to that win, left Santorum’s political operation earlier this year to manage Donald Trump’s political prospects in Iowa.

While Santorum’s 2012 campaign was marked by grassroots activism and a cash-strapped effort, he is looking to overcome the fundraising hurdles that sank his fortunes in 2012, forcing him to drop out.

He hired a new finance team early on to steer his fundraising efforts, a task led by Rob Bickhart, former finance director for the Republican National Committee. And heavyweight Republican donor Foster Friess, who helped bankroll Santorum’s 2012 effort, has already started his efforts to draw more money to Santorum’s new campaign.

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